
Plot
For years, Blade has fought against the vampires in the cover of the night. But now, after falling into the crosshairs of the FBI, he is forced out into the daylight, where he is driven to join forces with a clan of human vampire hunters he never knew existed—The Nightstalkers. Together with Abigail and Hannibal, two deftly trained Nightstalkers, Blade follows a trail of blood to the ancient creature that is also hunting him—the original vampire, Dracula.
Trailer
Cast

Wesley Snipes
Eric Brooks / Blade

Jessica Biel
Abigail Whistler

Ryan Reynolds
Hannibal King

Kris Kristofferson
Abraham Whistler

Dominic Purcell
Dracula / Drake

Parker Posey
Danica Talos

Natasha Lyonne
Sommerfield

James Remar
Ray Cumberland

John Michael Higgins
Dr. Edgar Vance

Patton Oswalt
Hedges

Callum Keith Rennie
Asher Talos

Paul Lévesque
Jarko Grimwood

Françoise Yip
Virago

Mark Berry
Chief Martin Vreede

Paul Anthony
Wolfe

Michael Anthony Rawlins
Wilson Hale

Ginger Page
Zoe

Eric Bogosian
Bentley Tittle

Erica Cerra
Goth Vixen Wannabe

Clay Cullen
Stone

Shannon Powell
Woman Bystander

Birkett Turton
Dingo

Brian Steele
Drake Creature (uncredited)

Christopher Heyerdahl
Caulder