The Substance

The Substance

If you follow the instructions, what could go wrong?

2024 en 141 minutes

Rating: 7.2

Plot

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Trailer

Cast

Demi Moore

Demi Moore

Elisabeth

Margaret Qualley

Margaret Qualley

Sue

Dennis Quaid

Dennis Quaid

Harvey

Edward Hamilton-Clark

Edward Hamilton-Clark

Fred

Gore Abrams

Gore Abrams

Oliver

Oscar Lesage

Oscar Lesage

Troy

Christian Erickson

Christian Erickson

Man at Diner

Robin Greer

Robin Greer

Male Nurse

Tom Morton

Tom Morton

Doctor

Hugo Diego Garcia

Hugo Diego Garcia

Diego - Boyfriend

Daniel Knight

Daniel Knight

Casting Director

Jonathon Carley

Jonathon Carley

Assistant Casting Director

Jiselle Henderkott

Jiselle Henderkott

Girl Auditioning / New Year's Eve Show Dancer

Akil Wingate

Akil Wingate

TV Host

Vincent Colombe

Vincent Colombe

Man in Suit #1 - Harvey's Office

Billy Bentley

Billy Bentley

Man in Suit #2

Lennard Ridsdale

Lennard Ridsdale

Man in Suit #3

Jordan Ford Silver

Jordan Ford Silver

Assistant Director - Pump It Up Show

Oscar Salem

Oscar Salem

2nd Assistant Director - Pump It Up Show

Viviane Bossina

Viviane Bossina

Sue's Assistant

Matthew Luret

Matthew Luret

Floor Runner

Jana Bittnerová

Jana Bittnerová

Maria

Olivier Raynal

Olivier Raynal

Alan - 2nd Agent

Tiffany Hofstetter

Tiffany Hofstetter

Stylist

Nicolas Royer

Nicolas Royer

Guy in the Elevator

Nathan Rippy

Nathan Rippy

Assistant Director - New Year's Eve Show

Manon Arizmendi

Manon Arizmendi

Little Girl - New Year's Eve Show

Virginie Kotlinski

Virginie Kotlinski

Mother - New Year's Eve Show

Brett Gillen

Brett Gillen

Director of Photography - New Year's Eve Show

Charlotte Marquardt

Charlotte Marquardt

Screaming Woman

Léa Hengl

Léa Hengl

Screaming Woman

Gaëlle Raymond

Gaëlle Raymond

Screaming Woman

Claire Lemaire

Claire Lemaire

Screaming Woman

Lila Boughoufala

Lila Boughoufala

Screaming Woman

Aurélien Lorgnier

Aurélien Lorgnier

Screaming Man

Ivan Sellier

Ivan Sellier

Screaming Man

Philip Schurer

Philip Schurer

Screaming Man

Christian Bourmier

Christian Bourmier

Shareholder

Martin Graham

Martin Graham

Shareholder

Christian Bordeleau

Christian Bordeleau

Shareholder

Patrick Hamel

Patrick Hamel

Shareholder

Didier Dhondt

Didier Dhondt

Shareholder

Jacques-Yves Dorges

Jacques-Yves Dorges

Shareholder

Jean-Claude Matthey

Jean-Claude Matthey

Shareholder

Olivier Jarcin

Olivier Jarcin

Shareholder

Jean-Luc Magneron

Jean-Luc Magneron

Shareholder

Charlotte Murray

Charlotte Murray

Allison - Diner Waitress

Aaron Kahn

Aaron Kahn

Greeting Person

Gabriela Arnon

Gabriela Arnon

Greeting Person

Nancy Josephson Lahoussine

Nancy Josephson Lahoussine

Greeting Person

Andrew Eldridge

Andrew Eldridge

Greeting Person

Denise Powers

Denise Powers

Greeting Person

Bryan Jones

Bryan Jones

Greeting Person

Adam Carage

Adam Carage

Happy Birthday Person

Maria McClurg

Maria McClurg

Happy Birthday Person

Andrew Desmond

Andrew Desmond

Happy Birthday Person

Rebecca Lafont

Rebecca Lafont

Happy Birthday Person

Laura Puech

Laura Puech

Isabella

Ryan Chidester

Ryan Chidester

Stagehand

Céline Vogt

Céline Vogt

Elisabeth (Young) - Walk of Fame

Yannick Guérin

Yannick Guérin

Clumsy Burger Guy - Walk of Fame

Jean Miel

Jean Miel

Worker Walk of Fame

Paul Descoings

Paul Descoings

Worker Walk of Fame

Benoit Lévêque

Benoit Lévêque

Worker Walk of Fame

Arthur Molinet

Arthur Molinet

Cocktail Bartender

Manon Sachot

Manon Sachot

Cocktail Lounge Couple

Bastien Jorelle

Bastien Jorelle

Cocktail Lounge Couple

Kelly Hoarau

Kelly Hoarau

Female Assistant - Towel

Michel Juskiewicz

Michel Juskiewicz

George - Harvey's Friend

Louise Greggory

Louise Greggory

Restaurant Waitress

Christophe Sartirano

Christophe Sartirano

Guy Looking at Sue

Florent Torres

Florent Torres

Guy Looking at Sue

Romain Caldeira

Romain Caldeira

Billboard Technician

Barthelemy Thomas

Barthelemy Thomas

Billboard Technician

Axel Baille

Axel Baille

Photographer

Ashley Lambert

Ashley Lambert

Additional Voices (voice)

Ranjani Brow

Ranjani Brow

Additional Voices (voice)

Chase Fein

Chase Fein

Additional Voices (voice)

Shane Sweet

Shane Sweet

Additional Voices (voice)

William Calvert

William Calvert

Additional Voices (voice)

Michael Corbett

Michael Corbett

Additional Voices (voice)

Stephen Apostolina

Stephen Apostolina

Additional Voices (voice)

Yann Bean

Yann Bean

The Substance (voice)

Audjyan Alcide

Audjyan Alcide

Pump It Up Show Dancer

Jonathan Jenvrin

Jonathan Jenvrin

Pump It Up Show Dancer

Mimi Maury

Mimi Maury

Pump It Up Show Dancer

Amelye Solange

Amelye Solange

Pump It Up Show Dancer

Kévin Table

Kévin Table

Pump It Up Show Dancer

Laura Boera

Laura Boera

Sparkle Your Life Show Dancer

Cissy Duc

Cissy Duc

Sparkle Your Life Show Dancer

Sophie Mercier

Sophie Mercier

Sparkle Your Life Show Dancer

Marie Valton

Marie Valton

Sparkle Your Life Show Dancer

Katrina Budzynski

Katrina Budzynski

New Year's Eve Show Dancer

Alicia Maury

Alicia Maury

New Year's Eve Show Dancer

Megane Adamik

Megane Adamik

New Year's Eve Show Dancer

Annalisa Pagnotta

Annalisa Pagnotta

New Year's Eve Show Dancer

Maelle Dantigny

Maelle Dantigny

New Year's Eve Show Dancer

Aleksandra Fontaine Kedzierska

Aleksandra Fontaine Kedzierska

New Year's Eve Show Dancer

Pauline Sagetat

Pauline Sagetat

New Year's Eve Show Dancer

Agustina Fitzsimons

Agustina Fitzsimons

New Year's Eve Show Dancer

Elena Shcheglova

Elena Shcheglova

New Year's Eve Show Dancer

Eve Marchant

Eve Marchant

New Year's Eve Show Dancer

Lola Donati

Lola Donati

New Year's Eve Show Dancer

Kate Matthews

Kate Matthews

New Year's Eve Show Dancer

Ophélie Jonard

Ophélie Jonard

New Year's Eve Show Dancer

Pauline Richard

Pauline Richard

New Year's Eve Show Dancer

Laureen Cappelliez

Laureen Cappelliez

New Year's Eve Show Dancer

Daria Panchenko

Daria Panchenko

New Year's Eve Show Dancer

Delphine Beaulieu

Delphine Beaulieu

New Year's Eve Show Dancer

Victoria Brun

Victoria Brun

New Year's Eve Show Dancer

Cara Chapman

Cara Chapman

New Year's Eve Show Dancer

Katharine Matthews

Katharine Matthews

New Year's Eve Show Dancer

Alexandra Faget

Alexandra Faget

New Year's Eve Show Dancer

Clémence Juville

Clémence Juville

New Year's Eve Show Dancer

Margot L'Entete

Margot L'Entete

New Year's Eve Show Dancer

Hillary Sukhonos

Hillary Sukhonos

New Year's Eve Show Dancer

Matthew Géczy

Matthew Géczy

Bob Haswell (uncredited)

Namory Bakayoko

Namory Bakayoko

Silhouette (uncredited)

Gregory Defleur

Gregory Defleur

Happy Birthday Person (uncredited)

Coralie Fargeat

Coralie Fargeat

(uncredited)

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